British Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike on an hidden munitions depot in Syrian territory employed by the IS group, as stated by the British defence ministry.
The site, pinpointed through surveillance, was believed to be housing weapons and explosive materials, the statement said, and was located in mountainous terrain just north of the ancient city of Palmyra in central Syria.
"Our fighter planes utilized Paveway IV guided bombs to target a series of approach shafts providing entry to the facility... initial indications suggest the objective was successfully hit," the ministry announced.
There was no sign of any harm to civilians in the strike late on Saturday and all the aircraft made a safe return, the ministry further stated.
The British jets were backed up by a Voyager aerial refuelling aircraft.
The Islamic State group - referred to as Daesh - imposed extremist governance over large swathes of both Syria and Iraq until 2019.
"This action demonstrates British leadership, and determination to operate in unison with allied nations, to stamp out any resurgence of the terrorist group and their dangerous and violent ideologies in the region," the British Defence Secretary the minister remarked.
British military aircraft have conducted overwatch operations over Syrian airspace to "prevent any efforts to regroup" of the group following its routing at the battle of Baghuz in 2019, the ministry said.
"I extend gratitude to all the members of the UK armed forces participating in this strike for their expertise and their bravery," the Defence Secretary said. "Including them were thousands of British troops deployed over the holidays. This action, to take out militants who pose a risk to our way of life, highlights how our armed forces are ready to step up, throughout the year, ensuring Britain's security at home and powerful internationally."
Last December, the American forces conducted what it described as a "major assault" against Daesh sites in Syria, after an attack killed two US troops and a local interpreter in the Palmyra area.
The U.N. reports Islamic State still maintains an estimated 5,000 to 7,000 fighters in Syria and Iraq.